The Effectiveness of Combining Ipratropium Bromide and Salbutamol for the Treatment of Acute Severe Exacerbation of Asthma in Children: A Literature Review
Ehab Aly Kilany Aly *
Danat Al Emarat Hospital, Abu Dhabi, United Arab Emirates.
*Author to whom correspondence should be addressed.
Abstract
The most common symptoms of asthma include episodes of wheezing, shortness of breath, and cough. When a person develops asthma in their childhood, it is usually seen to arise as a consequence of hay fever or allergic rhinitis and eczema, or atopic dermatitis. Maternal factors during the prenatal period have been found to be responsible to some extent in some infants, however, the role of breastfeeding and other nutritional allergies as the causes of asthma stands out to be unclear and controversial. The maintenance therapy of asthma in children comprises the following options, which are recommended to be used symptom-wise and only after keeping all the safety guidelines in mind. The combination therapy has been found to be very useful in treating asthma and reducing the complications that arise due to it.
Keywords: Combination therapy, asthma, atopic dermatitis, breastfeeding
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References
Hashmi MF, Tariq M, Cataletto ME. Asthma. In: Stat Pearls [Internet]. Treasure Island (FL): Stat Pearls Publishing; 2023. Available:http://www.ncbi.nlm.nih.gov/books/NBK430901/
Access on 2023 Jul 14.
Subbarao P, Mandhane PJ, Sears MR. Asthma: Epidemiology, etiology and risk factors. CMAJ Can Med Assoc J. 2009; 181(9):E181–90.
Dharmage SC, Perret JL, Custovic A. Epidemiology of asthma in children and adults. Front Pediatr [Internet]. 2019;7. Available:https://www.frontiersin.org/articles/10.3389/fped.2019.00246
Access on 2023 Jul 15.
Zar HJ, Ferkol TW. The global burden of respiratory disease-impact on child health. Pediatr Pulmonol. 2014;49(5):430–4.
Burke W, Fesinmeyer M, Reed K, Hampson L, Carlsten C. Family history as a predictor of asthma risk. Am J Prev Med. 2003;24(2):160–9.
Papandreou D, Pavlidou E, Tyrovolas S, Mantzorou M, Andreou E, Psara E, et al. Relation of maternal pre-pregnancy factors and childhood asthma: A cross-sectional survey in pre-school children aged 2-5 years old. Med Kaunas Lith. 2023;16; 59(1):179.
Davoodi P, Mahesh PA, Holla AD, Ramachandra NB. Family history & the risk for adult onset asthma. Indian J Med Res. 2015;141(3):361–3.
Levy ML. The national review of asthma deaths: what did we learn and what needs to change? Breathe. 2015;11(1):14–24.
Martin J, Townshend J, Brodlie M. Diagnosis and management of asthma in children. BMJ Paediatr Open. 2022;6(1): e001277.
Fleming M, Fitton CA, Steiner MFC, McLay JS, Clark D, King A, et al. Educational and health outcomes of children treated for asthma: Scotland-wide record linkage study of 683 716 children. Eur Respir J [Internet]. 2019;54(3).
Available:https://erj.ersjournals.com/content/54/3/1802309 Access on 2023 Jul 15.
Cusack RP, Satia I, O’Byrne PM. Asthma maintenance and reliever therapy: Should this be the standard of care? Ann Allergy Asthma Immunol off Publ Am Coll Allergy Asthma Immunol. 2020;125(2):150–5.
(PDF) Combined inhaled anticholinergics and short-acting beta 2 -agonists for initial treatment of acute asthma in children | Francine Ducharme and Benedict Griffiths - Academia.edu [Internet].
Available:https://www.academia.edu/32253211/Combined_inhaled_anticholinergics_and_short_acting_beta_2_agonists_for_initial_treatment_of_acute_asthma_in_children Access on 2023 Jul 16.
Aalbers R, Vogelmeier C, Kuna P. Achieving asthma control with ICS/LABA: A review of strategies for asthma management and prevention. Respir Med. 2016;111:1–7.
Kaplan A, Mitchell PD, Cave AJ, Gagnon R, Foran V, Ellis AK. Effective asthma management: Is It time to let the air out of SABA? J Clin Med. 2020;9(4): 921.
Iramain R, Castro-Rodriguez JA, Jara A, Cardozo L, Bogado N, Morinigo R, et al. Salbutamol and ipratropium by inhaler is superior to nebulizer in children with severe acute asthma exacerbation: Randomized clinical trial. Pediatr Pulmonol. 2019;54(4):372–7.
Xu H, Tong L, Gao P, Hu Y, Wang H, Chen Z, et al. Combination of ipratropium bromide and salbutamol in children and adolescents with asthma: A meta-analysis. PLoS ONE. 2021;16(2):e0237620.
Al-Turki A, Salvator A, Bai S, Sheikh SI. Comparison of two therapies on asthma control in children. Pediatr Allergy Immunol Pulmonol. 2020;33(3): 127–35.
Global Initiative for Asthma - GINA [Internet]. GINA Main Report; 2022. Available:https://ginasthma.org/gina-reports/
Access on 2023 Jul 15.