Health Related Quality of Life of Children Infected with HIV in Agra Region, India
Asian Journal of Pediatric Research,
Objective and Methods: HIV specific health related quality of life (HRQOL) instrument based on PedQLTM4.0 generic scale was prepared and named HIV-QOL. It was validated and used to evaluate HRQOL in HIV infected children in an observational,crossectional study conducted in the Department of Pediatrics, Sarojini Naidu Medical College, Agra, India.
Results:Cronbach’s alpha score > 0.7,supported acceptable internal consistency of the instrument.The correlation coefficient of more than 0.8 indicated that the instrument was valid for application. Study included 40 HIV infected children between age 8 to 18 years.Their mean scores were calculated in all four domains (viz physical, social, emotional and school functioning) and comparison of HRQOL scores was done with respect to various social and demographic parameters. CD4 counts, clinical stage of the disease and living status of the parents and anti retroviral therapy (ART) had significant influence on the HRQOL scores.
Conclusion: HIV QOL is a valid instrument to assess the health related quality of life of HIV infected children in India. It can help in assessing their health status, as well as in evaluating the impact of various medical and social programmes aimed at improving their quality of life.
- Quality of life
How to Cite
MissmerSA, Spiegleman D, Sherwood L. Predictors of change in the functional status of children with human immunodeficiency viral infection. Pediatrics.2000;106(2):e24-e30.
Wallender JL, VarniJW. Effects of Pediatric Chronic Physical Disorders on Child and Family Adjustment. Journal of Child Psychology and Psychiatry. 1998;39(1):29-46.
Garvie PA, Lawford J, Banet MS, West RL. Quality of life measurement in paediatric and adolescent populations with HIV: A review of the literature. Child: Care, Health and Development. 2009;35(4):440-453.
Cleary PD, Fowler FJ Jr, Weissman J, Massagli MP, Wilson I, Seage GR 3rdet al. Health-related quality of life in persons with acquired immune deficiency syndrome. Med Care 1993;31(7):569-80
Banerjee T. Pensi T. Banerjee D. HRQoL in HIV-infected children using PedsQL 4.0 and comparisons with uninfected children. Quality of Life Research. 2010;19:803-812.
Bomba M,Nacinovitch R, Oggiano S, Cassani M,Baushi L,Bertulli C,Longhi D,Coppini S,Parrinello G,Plebani A,Badolato R. Poor health-related quality of life and abnormal psychological adjustment in Italian children with perinatal HIV infection receiving highly active antiretroviral treatment. AIDS Care. 2010;22(7):858-865
Das A, Detels R, Afifi AA, Javanbakht M, Sorvillo F, Panda S. Formation and psychometric evaluation of a health-related quality of life instrument for children living with HIV in India. J Health Psychol. 2018;23(4):577-587.
Punpanich W, Hays RD, Detels R, et al. Development of a culturally appropriate health-related quality of life measure for human immunodeficiency virus-infected children in Thailand. J Paediatr Child Health. 2011;47(1-2):27-33.
Nicolas J, Dazord A, Manificat S. Evaluation of life quality for children infected by HIV: validation of a method and preliminary results. Pediatr AIDS HIV Infect. 1996;7(4):254-60.
Pediatric Quality of life inventory version 4.0 (PedsQL 4.0)-Dr James W Varni, Mapi research trust Lyon, France, with due permission; 1998.
Varni JW,Seid M,Kurtin PS. PedsQL 4.0: Reliability and Validity of the Pediatric Quality of Life Inventory Version 4.0 Generic Score Scales in Healthy and Patient Populations. Medical Care. 2001;39(8):800 – 812.
Patro BK, Jeyashree K, Gupta PK. Kuppuswamy’s Socioeconomic Status Scale 2010—The Need for Periodic Revision. Indian J Pediatr. 2012;79:395–6.
CronbachL. coefficient alpha and the internal structure of test. Psychometrika. 1951;16(3):297-334
Gliem JA, Gliem RR. Calculating, interpreting and reporting cronbach’s alpha reliability coefficient for likert scales. Presented at Midwest research to practice conference in adults, continuing and community education, Ohio state university ,Columbus OH; 2003.
WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adults and children. World Health Organisation; 2007.
Xu T, Wu Z, Rou K,Duan S, Wang H. Quality of Life of children living with HIV/AIDS-affected families in rural areas in Yunnan, Acahina. AIDS Care. 2010;22(3):390-396.
Linda Aurpibul, PeninnahOberdorfer, WorawutChoeyprasert, OrawanLouthrenoo Health-related quality of life of perinatally HIV-infected adolescents.Curr. Pediatr.Res 2016;20(1&2):231-237.
Gupta M, Nanda S, Kaushik JS. Quality of life in symptomatic HIV infected children. Indian Pediatr. 2013;50:1145-1147.
Imam MH, Karim MR, Ferdous C, Akhter S, Health related quality of life among the people living with HIV. Bangladesh Medical Research Council Bulletin. 2011;37:1-6.
Punpanich W, Boon-Yasidhi V, Chokephaibulkit K, et al. Health-related Quality of Life of Thai children with HIV infection: A comparison of the Thai Quality of Life in Children (ThQLC) with the Pediatric Quality of Life Inventory™ version 4.0 (PedsQL™ 4.0) Generic Core Scales. Qual Life Res. 2010;19(10):1509-1516.
Oberdorfer P, Louthrenoo O, Puthanakit T, Sirisanthana V, Sirisanthana T. Quality of Life among HIV Infected Children in Thailand. Journal of the International Association of Physicians in AIDS Care. 2008;141-151.
Bunupuradah T, Kosalaraksa P, Vibol U, et al. Predict study group. Impact of antiretroviral therapy on quality of life in HIV-infected Southeast Asian children in the PREDICT study. AIDS Patient Care STDS. 2013;27:596-603.
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