Incidence of Neonatal Convulsion/Seizures Associated with Primary Disturbance of Calcium, Phosphorus, and Magnesium in University of Port Harcourt Teaching Hospital (UPTH)
Asian Journal of Pediatric Research,
Page 26-34
DOI:
10.9734/ajpr/2022/v8i330246
Abstract
Neonatal seizures are abnormal electrical discharge in the neonates that usually manifest as stereotyped muscle activity of autonomic change. Seizure occur in up to 1.4% of mature infant and 20% of pre-mature infant. Neonate in university of Port Harcourt Teaching Hospital were used for the study, 86 blood samples were collected from the children department, the children include both male and female within the Age range of I day to 7 day. Out of the total of 86 sample analyzed for calcium, magnesium and Phosphorus from the results obtained from both calcium and magnesium failed below the reference value, that indicate that calcium and magnesium where the major causes of the neonatal seizures.
Keywords:
- Neonatal seizure
- electrolytes
- calcium
- magnesium
How to Cite
Ogheneochuko Eruotor, H., Blessing, U., E. Ajirioghene, A., Awarajih Uwaezuoke, C., & Ignatius Chinonye, N. (2022). Incidence of Neonatal Convulsion/Seizures Associated with Primary Disturbance of Calcium, Phosphorus, and Magnesium in University of Port Harcourt Teaching Hospital (UPTH). Asian Journal of Pediatric Research, 8(3), 26-34. https://doi.org/10.9734/ajpr/2022/v8i330246
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Mcinerney TK, Schubert WK. Pronosis of neonatal seizures American Journal of Diseases of Children. 2008;117:261.
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Paunier L, Radde IC, koob SW, Fraser D. Primary hypomagnesemia with secondary hypocalcemia. (Abst) Journal of Pediatrics. 1965;67:945.
Zimmet P, Breidahi HD, Nayler WG. Plasma conized calcium in Hypomagnesaemia. British Medical Journal. 1968;1:622.
Keen JH. Significance of hypocalcaemia in neonatal convulsions. Archives of Disease in Childhood. 1969;44:356.
Craig WS. Convulsive movements occurring in the first ten days of life; 1960.
Eades S. Hypocalcaernic fits in neonates; 1968.
Engel RR, Elm RJ. Hypermagnesemia from birth asphyxia. Journal of Pediatrics. 2004;77:631.
Fanconi G, Prader A. Transient congenital idiopwthic hypoparaathyroidism. Helvetica Paediatrlca Acta. 1967;22:342.
Gittleman LF, Pinkus JB, schmerztler E. Interrelationship of calcium and magnesium in the mature neonate. American Journal of Diseases of Children. 1964;107.
Harris, Tizard JPM. The electre encepphalogram in neonatal convulsions. Journal of Pediatrics. 1960;57:501.
Heaton FW, Fourman P. Magnesium deficiency and hypocalcaeniia in intestinal malabsorption. Lancet. 1965;2(50):55.
Huggett AstG, Nixon DA. Enzymic determination of blood glucose (Abst). Biochemical Journal. 1957;66:12.
Khattab AK, Forfar JO. Jntcrrclatioln 3 hip of calcium, phosphorus and glucose levels in mother and newborn infant. Biology of the Neonate. 1970;15:26.
Paunier L, Radde IC, koob SW, Fraser D. Primary hypomagnesemia with secondary hypocalcemia. (Abst) Journal of Pediatrics. 1965;67:945.
Prechtl HFR, Bentema DJ. The Neurdogical Examination of the full -Term newborn infant. Clinics in Developmental medicine, No 12. Heinemann, London; 1964.
Thigh RJ. Hypocalcaemic Fit in neonates A study follow-up. Pediatrics. 1968;45: 404.
Pugh RJ. Hypocalcaemic Fits in neonates. Lancet. 1968;1:644.
Salat JC, Polonovski C, de Govyon F, Pean O, Melekian, Fournet J. Tetanic hypocalcaemic Rchdivante par hypomagnesemic longenitace. Archives Francaises de Pediatric. 1966;23:749.
Seelig M. Human requirements of magnesium Factors that increase need. Proceedings of the 1 st international symposium on magnesium Deficit in Human pathology, P.11. Ed. ByJ. Durlach; 1971.
Thomson 3. Clinical study and Treatment of sick children, 4th ed. Oliver and Boyd, Edinburgh and London; 1925.
Wallach S, Carter AC. Metabolic and renal effects of acute hypercalcemia in dogs. American Journey of Physiology. 1961;200:359.
Wateny PJM, Chance GW, Scolt PC, Thompson JM. Maternal factors in neonatal hypocalcaemia a study in three ethnic groups. British medical Journey. 1971;2:432.
Correspondence to Professor J.O. Forfar, Department of child Life and Health, 17 Hatton place, Edinburgh EHA IUW.
Craig WS. Convulsive movements occurring in the first ten days of life; 1960.
Jensen FE. Neonatal seizures: An update on mechanisms and management. Clinics in perinatology. 2009;36(4):881–vii. Available:https://doi.org/10.1016/j.clp.2009.08.001
Schwartz JF. Neonatal convulsions. Clinical Pediatrics. 1965;4:595.
Freeman JM. Neonatal seizures-dragnesis and management. Journal Padiatrics. 2001;77:701.
Rose Al, Lombroso CT. A study of clinical, pathological, and electroencephalographic features in 137 full-term babies with a long-term follow-up padiatrics. 1970;45:404.56.
Mcinerney TK, Schubert WK. Pronosis of neonatal seizures American Journal of Diseases of Children. 2008;117:261.
Paunier L, Radde IC, koob SW, fraser D. Primary hypomagnesemia with secondary hypocalcemia. (Abst) Journal of Pediatrics. 1965;67:945.
Paunier L, Radde IC, koob SW, Fraser D. Primary hypomagnesemia with secondary hypocalcemia. (Abst) Journal of Pediatrics. 1965;67:945.
Zimmet P, Breidahi HD, Nayler WG. Plasma conized calcium in Hypomagnesaemia. British Medical Journal. 1968;1:622.
Keen JH. Significance of hypocalcaemia in neonatal convulsions. Archives of Disease in Childhood. 1969;44:356.
Craig WS. Convulsive movements occurring in the first ten days of life; 1960.
Eades S. Hypocalcaernic fits in neonates; 1968.
Engel RR, Elm RJ. Hypermagnesemia from birth asphyxia. Journal of Pediatrics. 2004;77:631.
Fanconi G, Prader A. Transient congenital idiopwthic hypoparaathyroidism. Helvetica Paediatrlca Acta. 1967;22:342.
Gittleman LF, Pinkus JB, schmerztler E. Interrelationship of calcium and magnesium in the mature neonate. American Journal of Diseases of Children. 1964;107.
Harris, Tizard JPM. The electre encepphalogram in neonatal convulsions. Journal of Pediatrics. 1960;57:501.
Heaton FW, Fourman P. Magnesium deficiency and hypocalcaeniia in intestinal malabsorption. Lancet. 1965;2(50):55.
Huggett AstG, Nixon DA. Enzymic determination of blood glucose (Abst). Biochemical Journal. 1957;66:12.
Khattab AK, Forfar JO. Jntcrrclatioln 3 hip of calcium, phosphorus and glucose levels in mother and newborn infant. Biology of the Neonate. 1970;15:26.
Paunier L, Radde IC, koob SW, Fraser D. Primary hypomagnesemia with secondary hypocalcemia. (Abst) Journal of Pediatrics. 1965;67:945.
Prechtl HFR, Bentema DJ. The Neurdogical Examination of the full -Term newborn infant. Clinics in Developmental medicine, No 12. Heinemann, London; 1964.
Thigh RJ. Hypocalcaemic Fit in neonates A study follow-up. Pediatrics. 1968;45: 404.
Pugh RJ. Hypocalcaemic Fits in neonates. Lancet. 1968;1:644.
Salat JC, Polonovski C, de Govyon F, Pean O, Melekian, Fournet J. Tetanic hypocalcaemic Rchdivante par hypomagnesemic longenitace. Archives Francaises de Pediatric. 1966;23:749.
Seelig M. Human requirements of magnesium Factors that increase need. Proceedings of the 1 st international symposium on magnesium Deficit in Human pathology, P.11. Ed. ByJ. Durlach; 1971.
Thomson 3. Clinical study and Treatment of sick children, 4th ed. Oliver and Boyd, Edinburgh and London; 1925.
Wallach S, Carter AC. Metabolic and renal effects of acute hypercalcemia in dogs. American Journey of Physiology. 1961;200:359.
Wateny PJM, Chance GW, Scolt PC, Thompson JM. Maternal factors in neonatal hypocalcaemia a study in three ethnic groups. British medical Journey. 1971;2:432.
Correspondence to Professor J.O. Forfar, Department of child Life and Health, 17 Hatton place, Edinburgh EHA IUW.
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