Asian Journal of Pediatric Research

Is HO-YAG Laser in Perianal Warts Safe in Children? A Report of 3 Cases

Merve Altin Gulburun — 2021-07-23

Verruca Vulgaris or wart is a common skin disease caused by human papillomavirus (HPV) infection. Warts are usually located on fingers, hands, elbows and feet. Anogenital region is an uncommon location for warts. Three children with large perianal warts were treated by holmium: Yttrium Aliminum Garnet (Ho-YAG) laser. No recurrences or significant complications were seen in 2 years of follow up period. Ho-YAG Laser was successfully applied in the treatment of pediatric perianal warts. It is a safe and effective method.

Clinical Profiling of a Chicken Based Formula in an Indian Children’s Hospital

Dhanasekhar Kesavelu — 2021-07-23

Aims: To compare nutritional status of chronic ill children before and after using chicken-based formula (CBF).

Design: A retrospective, case note based, observational study of the use of CBF in various clinical indications were noted and results critically analysed.

Study Design: In this study, out patients aged 1 to 36 months who were prescribed CBF from 2018-2020 were included. The indications for using the formula and the outcomes were noted. All subjects, consumed the prescribed formula for a minimum of six months. The pre and post - therapy nutritional status were assessed. The collected data was analysed using SPSS Version 20.

Methodology: Children between the ages 1 to 36 months who presented with chronic diarrhoea in whom CBF was prescribed either as primary source of nutrition or an nutritional adjunct were included in the study. Children who were allergic to the CBF or any of its ingredients were excluded from the study.

Results: 34 children were prescribed CBF for various indications including Cow’s milk protein allergy (n=18, 52%), underweight (n=8, 23.5%), Chronic Diarrhoea (n=8, 23.5%). The age range was 0-6 months n=13 (38.2%), 6-12 months n=14 (41.2%) and 12-36 months=7 (20.6%).The nutritional assessment prior to commencing feeds showed 52.9% (n=18) were underweight, 44.1% (n=15) were well nourished and 2.9% (n=1) was overweight. Post feeding nutritional status showed-20.58% (n= 7) remained underweight, 76.4% (n=26) were well nourished and 2.9 % (n= 1) overweight. Weight gain was significant in selected subjects (<.001).Pearson correlation indicates that there was significant positive correlation between CBF and weight gain.

Conclusions: Growth parameters of infants fed with CBF matches with infants who are not fed on CBF. CBF can be used as an alternative in the absence of equivalent therapeutic feeds. It may be used for indications such as secondary lactose intolerance, celiac disease, malnutrition and alternative to hypo-allergenic formula (as a cheaper and cost effective formula) and as an adjuvant in malnutrition.

Study of Serum Vitamin D Levels in Children with Immune Thrombocytopenic Purpura

Mina Fayez Anes Karaz — 2021-07-27

Background: Immune thrombocytopenic purpura (ITP) is described by an immune responding versus the host’s own platelets, in recent years is progressively studied the non-calcemic roles of vitamin-D (VD) that controls immune and inflammation responding.

Aim and objectives: The current work aimed to study VD-level in children with ITP and influence of VD supplementing upon the responding of the thrombopenia to conventional therapy of ITP. Subjects and methods: This study is a cross-sectional observational work which included 30 ITP-children who were attendants to Hematology and Oncology Unit, Pediatric Department, Tanta University Hospitals with ages from 2 to 16-yrs with mean ageing of 6.43 ± 3.75-yrs, for all patients and controls serum-levels of 25-hydroxyvitamin D (25[OH]D) were measured.

Results: A significant change was found among the studied groups in regard to VD-levels with lower values among patients compared with controls, a statistically significant negative association was found among platelet counts and each of vitamin D level and serum Ca, the mean platelet count after conventional therapy was significantly increased in group one ITP patients. Conclusion: VD lack is very frequent in children with recently identified or chronic ITP form. Consequently, there are advantages of supplement VD in ITP-cases.