Open Access Case Report

Is HO-YAG Laser in Perianal Warts Safe in Children? A Report of 3 Cases

Merve Altin Gulburun, Hayrunnisa Oral, Sibel Eryilmaz, Cem Kaya, Ramazan Karabulut, Zafer Turkyilmaz, Kaan Sonmez

Asian Journal of Pediatric Research, Page 1-4
DOI: 10.9734/ajpr/2021/v6i230189

Verruca Vulgaris or wart is a common skin disease caused by human papillomavirus (HPV) infection. Warts are usually located on fingers, hands, elbows and feet. Anogenital region is an uncommon location for warts.  Three children with large perianal warts were treated by holmium: Yttrium Aliminum Garnet (Ho-YAG) laser. No recurrences or significant complications were seen in 2 years of  follow up period.  Ho-YAG Laser was successfully applied in the treatment of pediatric perianal warts. It is a safe and effective method.

Open Access Original Research Article

Clinical Profiling of a Chicken Based Formula in an Indian Children’s Hospital

Dhanasekhar Kesavelu, V. S. Lekha

Asian Journal of Pediatric Research, Page 5-11
DOI: 10.9734/ajpr/2021/v6i230190

Aims: To compare nutritional status of chronic ill children before and after using chicken-based formula (CBF).

Design: A retrospective, case note based, observational study of the use of CBF in various clinical indications were noted and results critically analysed.

Study Design: In this study, out patients aged 1 to 36 months who were prescribed CBF from 2018-2020 were included. The indications for using the formula and the outcomes were noted. All subjects, consumed the prescribed formula for a minimum of six months. The pre and post - therapy nutritional status were assessed. The collected data was analysed using SPSS Version 20.

Methodology: Children between the ages 1 to 36 months who presented with chronic diarrhoea in whom CBF was prescribed either as primary source of nutrition or an nutritional adjunct were included in the study. Children who were allergic to the CBF or any of its ingredients were excluded from the study.

Results: 34 children were prescribed CBF for various indications including Cow’s milk protein allergy (n=18, 52%), underweight (n=8, 23.5%), Chronic Diarrhoea (n=8, 23.5%). The age range was 0-6 months n=13 (38.2%), 6-12 months n=14 (41.2%) and 12-36 months=7 (20.6%).The nutritional assessment prior to commencing feeds showed 52.9% (n=18) were underweight, 44.1% (n=15) were well nourished and 2.9% (n=1) was overweight. Post feeding nutritional status showed-20.58% (n= 7) remained underweight, 76.4% (n=26) were well nourished and 2.9 % (n= 1) overweight. Weight gain was significant in selected subjects (<.001).Pearson correlation indicates that there was significant positive correlation between CBF and weight gain.

Conclusions: Growth parameters of infants fed with CBF matches with infants who are not fed on CBF. CBF can be used as an alternative in the absence of equivalent therapeutic feeds. It may be used for indications such as secondary lactose intolerance, celiac disease, malnutrition and alternative to hypo-allergenic formula (as a cheaper and cost effective formula) and as an adjuvant in malnutrition.

Open Access Original Research Article

Study of Serum Vitamin D Levels in Children with Immune Thrombocytopenic Purpura

Mina Fayez Anes Karaz, Sarah Amr Hamam, Ibrahim Mohamed Badraia, Adel Abd El-Haleim Hagag

Asian Journal of Pediatric Research, Page 12-18
DOI: 10.9734/ajpr/2021/v6i230191

Background: Immune thrombocytopenic purpura (ITP) is described by an immune responding versus the host’s own platelets, in recent years is progressively studied the non-calcemic roles of vitamin-D (VD) that controls immune and inflammation responding.

Aim and objectives: The current work aimed to study VD-level in children with ITP and influence of VD supplementing upon the responding of the thrombopenia to conventional therapy of ITP. Subjects and methods: This study is a cross-sectional observational work which included 30 ITP-children who were attendants to Hematology and Oncology Unit, Pediatric Department, Tanta University Hospitals with ages from 2 to 16-yrs with mean ageing of 6.43 ± 3.75-yrs, for all patients and controls serum-levels of 25-hydroxyvitamin D (25[OH]D) were measured.

Results: A significant change was found among the studied groups in regard to VD-levels with lower values among patients compared with controls, a statistically significant negative association was found among platelet counts and each of vitamin D level and serum Ca, the mean platelet count after conventional therapy was significantly increased in group one ITP patients. Conclusion: VD lack is very frequent in children with recently identified or chronic ITP form. Consequently, there are advantages of supplement VD in ITP-cases.

Open Access Original Research Article

Comparison Between Score for Neonatal Acute Physiology Perinatal Extension II and Clinical Risk Index for Babies in Prediction of Neonatal Mortality in Septic Preterm Cases Tanta University Hospital’s Neonatal Intensive Care Unit

Ahmed Hossam El-Din Abd Al-fatah Al-Akhd, Ashraf Mohamed Ibrahim, Nihal Salah El-Din Shihab, Heba Said El Mahdy

Asian Journal of Pediatric Research, Page 19-26
DOI: 10.9734/ajpr/2021/v6i230192

Background: Preterm birth (< 37 weeks gestation) is a major cause of death and a significant cause of long-term loss of human potential amongst survivors all around the world.

Aim: Compare between two neonatal mortality risk scores, Score for neonatal acute physiology perinatal extension (SNAP-PE II) and Clinical risk index for babies (CRIB), in predicting the neonatal mortality in septic preterm admitted to neonatal intensive care unit (NICU) of Tanta University Hospital (TUH) over a period of one year.

Patients and Methods: This was a prospective cohort study carried out on 200 septic preterm newborns admitted to NICU of TUH over 1 year period. 89 cases representing (44.5 %) were female and 111 cases representing (55.5%) were male. All of them were admitted to NICU [within their first 48 hours of birth]. All septic preterm neonates will be followed up till their death or discharge. SNAP-PE II and CRIB scores applied to all the septic preterm neonates in this study during the first 12 hours after diagnosis of sepsis in NICU according to Modified Hematological scoring system (MHSS).

Results: There was a weak positive correlation between MHSS score for neonatal infection and both of the SNAP II and CRIB scores.

Conclusion: Both SNAP-PE II and CRIB scores have good sensitivity for predicting neonatal mortality which was slightly higher in SNAPPE II score. Neonatal Mortality rate was significantly correlated with high MHSS.

Open Access Original Research Article

Evaluation of Parent's Knowledge About Fever

Najlae El Hafidi, Nour Mekaoui, Badr Sououd Benjelloun Dakhama, Lamya Karboubi

Asian Journal of Pediatric Research, Page 27-35
DOI: 10.9734/ajpr/2021/v6i230193

Introduction: Fever in children is the most frequent reason for pediatric consultation. Aims of the Study: To assess parent's knowledge and behavior regarding fever in children before the consultation.

Methodology: This survey was carried out among 614 who agreed to answer a pre-established questionnaire, having consulted in the pediatric medical emergency department of the children's hospital in rabat.

Results: Fever was defined in 64.2% of parents as a temperature above the threshold of 38 ° C. It was measured in 37.9% of cases by the axillary method, the drugs most used were paracetamol and ibuprofen, with the use of paracetamol first in 73.9%, the administration of the drug was based of the weight in 58.7%. Angina was considered the most likely cause of fever (72.7% of cases).

Conclusion: The results of our survey show the need to improve parent's knowledge of fever as well as its management at home.