Open Access Case Report

Retropharyngeal Abscess Presenting as Stridor in a 35 Days Male Infant: A Case Report

Achinta Kumar Mallick, Abhishek Mishra, Pravin Kumar Yadav, Anushree Mishra

Asian Journal of Pediatric Research, Page 10-14
DOI: 10.9734/ajpr/2022/v8i330243

Retropharyngeal abscess (RPA) is a rare entity in infants. There is limited knowledge and literature available about RPA in neonates and young infants owing to its atypical presentation, often causing a diagnostic dilemma to the treating physicians. RPA should always be kept in mind for all infants presenting with upper respiratory tract symptoms. Proper history, meticulous clinical examination and a very high index of suspicion is key to its prompt diagnosis. There is always a risk of airway compromise in neonates and young infants, owing to the narrow airway and an early surgical intervention is mandatory. We hereby present a rare case of RPA in a 35 day old male infant having atypical presentation of stridor and sepsis. Timely radiological evaluation in form of ultrasonography (USG) & contrast enhanced computerized tomography (CECT) neck was instrumental not only in prompt diagnosis but also in immediate decompression drainage of abscess which turned out to be lifesaving. 

Open Access Case Study

Drug-resistant Epilepsy Revealing Pseudo-hypoparathyroidism

M. Kabbaj, S. Amhagar, Y. Kriouil

Asian Journal of Pediatric Research, Page 22-25
DOI: 10.9734/ajpr/2022/v8i330245

Pseudohypoparathyroidism (PHP) is a very rare disease, due to genetic abnormalities of variable expressivity, resulting in resistance of target tissues to the action of parathyroid hormone (PTH). It is a disease that presents in several varieties depending on the existence or not of dysmorphic syndrome, resistance to other hormones and on the responses of hormonal signaling pathways to exogenous PTH supply. Fahr's syndrome is one of the consequences of pseudohypoparathyroidism, it is defined by the presence of intracerebral calcifications, bilateral and symmetrical, non arteriosclerotic, located in the basal ganglia. We report in this work, the observation of a 12 years old child, suffering from a PHP complicated with a Fahr syndrome, discovered after several years of evolution of persistent neurological disorders and refractory to treatments. This work underlines the interest of the research of the disorders of the phosphocalcic metabolism in the presence of neuropsychiatric demonstrations, in order to detect a PHP or any other etiology of a syndrome of Fahr and to adopt thus, the most appropriate therapeutic measures.

Open Access Original Research Article

Institutional Analysis of the Bacteriological Profile and Antibiotic Susceptibility of the Neonatal Sepsis in Eastern Nepal

Ramesh Prasad Das, Pankaj Kumar Thadhiya Yadav, Rambabu Yadav, Sadaf Saleem Sheikh, Dipak Kumar Yadav

Asian Journal of Pediatric Research, Page 15-21
DOI: 10.9734/ajpr/2022/v8i330244

Introduction: In the developing nations, neonatal sepsis account for the larger portion of the neonatal morbidity and mortality. Blood culture is considered as the gold standard for the diagnosis. Both, the conformation and management is difficult for clinicians in the resource limited nations like Nepal.

Method: It is a retrospective observational study conducted at one of the tertiary care hospital in eastern Nepal over a year.

Result: Incidence of neonatal sepsis was 12.9%. The incidence of blood culture positivity in the neonatal sepsis was 15%. Coagulase negative Staphylococcus species and Escherichia coli were two most predominant organism isolated. All of the isolated Klebsiella spp. and Pseudomonas spss.showed resistance to ampicillin whereas 100% of Coagulase Negative Staphylococcus spp. showed sensitivity to vancomycin.

Conclusion: Isolated bacteria showed resistance to multiple antibiotics. This is an alarming moment for the pediatrician. Antibiotics should be used judiciously and continuous surveillance should be done to monitor the changing epidemiology of organisms and antibiotic sensitivity as the emergence of resistance to commonly used antibiotics is high.

Open Access Original Research Article

Incidence of Neonatal Convulsion/Seizures Associated with Primary Disturbance of Calcium, Phosphorus, and Magnesium in University of Port Harcourt Teaching Hospital (UPTH)

Harrison Ogheneochuko Eruotor, Ukoro Blessing, Akpotu E. Ajirioghene, C. Awarajih Uwaezuoke, Nduka Ignatius Chinonye

Asian Journal of Pediatric Research, Page 26-34
DOI: 10.9734/ajpr/2022/v8i330246

Neonatal seizures are abnormal electrical discharge in the neonates that usually manifest as stereotyped muscle activity of autonomic change. Seizure occur in up to 1.4% of mature infant and 20% of pre-mature infant. Neonate in university of Port Harcourt Teaching Hospital were used for the study, 86 blood samples were collected from the children department, the children include both male and female within the Age range of I day to 7 day. Out of the total of 86 sample analyzed for calcium, magnesium and Phosphorus from the results obtained from both calcium and magnesium failed below the reference value, that indicate that calcium and magnesium where the major causes of the neonatal seizures.

Open Access Review Article

Overview on the Causes and Management of Neonatal Meningitis

Wadah Faisal Elmihana, Nazim Faisal Hamed, Abdulaziz Sael M. Alshammari, Atheer Ayed Alenezi

Asian Journal of Pediatric Research, Page 1-9
DOI: 10.9734/ajpr/2022/v8i330242

In comparison to other ages, neonatal meningitis is more prevalent. Because the immature immune system lacks humoral and cellular immunological responses in phagocytic and complement functions, the newborn is especially vulnerable to infection. According to the World Health Organization, almost 5 million newborn fatalities occur each year. The great majority of them (98%) take place in underdeveloped countries. Meningitis is diagnosed through a physical examination and a study of the patient's medical history for any of the symptoms listed above. Although patients with viral meningitis normally do not require hospitalisation, antipyretics, antiemetics, and analgesics that may be used at home should be offered.