Open Access Original Research Article
Background: Serological testing is urgently required since COVID-19 is the pandemic that is spreading the fastest in recent times, Although RT-PCR is an effective and specific method for diagnosing acute patients, serological tools are urgently required for examining antibody responses and evaluating both individual and prospective herd immunity. The aim of this study was divided into primary objectives were to assess serum IgM antibodies for SARS-Cov-2 in febrile children attending ER in Tanta University Hospital and secondary objectives were to assess computed tomography (CT) findings in febrile SARS-Cov-2 IgM antibody-positive individuals.
Methods: This cross-section study was carried out on sixty children presented by fever with any respiratory symptom as cough and dyspnea and fever with non-respiratory and cutaneous symptoms. The patients were divided into three equal groups: group 1: included healthy children, group 2: included febrile children with respiratory symptoms as cough and dyspnea and group3: included febrile children with fever alone or with non-respiratory symptoms as Gastrointestinal symptoms as vomiting and diarrhea, cutaneous manifestations as rash, and CNS manifestations.
Results: IgM were significantly higher in group II compared to other groups, significantly higher in group III compared to group I (P value <0.001).CO-RADS 2,4 and 5 were significantly higher in group II compared to other groups, CO-RADS 3 was insignificantly different between groups II and III. Patients with positive CXR at time of presentation were significantly higher in group II compared to other groups. (P value 0.005).
Conclusions: In children with COVID-19, Serum IgM to SARS-COV-2 was significantly higher in febrile children in Tanta University during the period from March 2021 to February 2022. According to CT findings, CO-RADS 2,4 and 5 were significantly higher in febrile patients with positive SARS-Cov-2 serum Igm Ab.
Open Access Original Research Article
Background: Neonatal mortality rate is an important indicator which does not only reflect the overall health of a child and well-being but also assesses the social and economic development of a country.
Aim: The study was carried out to determine the pattern and factors associated with neonatal mortality.
Methods and Materials: It was a retrospective study carried out in the Special care Baby Unit of the Rivers State University Teaching Hospital from January 2016 to December 2020.
Results: Of 2,944 neonatal admissions, 358 died giving a mortality of 12.2% with male preponderance (M:F ratio of 1.5:1). Majority of the neonates who died were admitted within the first 24 hours of life 289(80.7%) and were delivered via Caesarean section 195(54.4%). Most deaths occurred in the first 7 days of life 189(52.8%). The commonest cause of mortality was neonatal sepsis 183 (51.1%) followed by perinatal asphyxia 178(49.7%) and prematurity 176(49.2%). Most mortalities occurred between 4.00pm and 7.59 am 218(61.0%) outside regular work hours. The lowest annual mortality was recorded in the year 2020 (6.36%) while the highest was in the year 2018 (19.27%). There was significant mortality within 24hours of admission among neonates < 1.5 kg as well as those with sepsis, anaemia and neonatal jaundice.
Conclusion: The mortality rate of neonates in the Rivers State University Teaching Hospital was high, 12.2% with neonatal sepsis, perinatal asphyxia and prematurity being the commonest causes which are largely preventable. There is therefore need to improve obstetric and newborn care to improve neonatal outcome.
Open Access Review Article
Outpatient therapeutic programme (OTP) is one of the approaches of community-based management of acute malnutrition (CMAM), which includes community engagement and mobilization for outpatient management of uncomplicated severe acute malnutrition (SAM) children 6–59 months with good appetite, by providing them by home-based treatment as Ready-to-use Therapeutic Food (RUTF) and routine medical treatment. Around 85-90% of children with SAM are successfully treated at home in OTP, by attending regular intervals until they recover. OTP is currently used to achieve rapid recovery from SAM, it provides services of SAM management closer to the community at primary health care centers, where uncomplicated SAM children receive different amount of RUTF as Plumpy'Nut sachets according to their body weight.