Risk Factors Associated with Acute Renal Failure in Neonates of a neonatal Intensive Care Unit
Ana Jaqueline Uribe Barrera
Departamento de Neonatología, Secretaría de Salud de Hidalgo, Pachuca Hidalgo, México.
Ana Isabel Valenzuela de la Cueva
Departamento de Neonatología, Secretaría de Salud de Hidalgo, Pachuca Hidalgo, México.
Claudia Teresa Solano Pérez
Departamento de Medicina de la Universidad Autónoma del Estado de Hidalgo, Pachuca, México.
Saraí Martínez Llergo
Departamento de Salud Pública de la Universidad Autónoma del Estado de Hidalgo, Pachuca, México.
Sinaí Hinojosa Hernández
Departamento de Salud Pública de la Universidad Autónoma del Estado de Hidalgo, Pachuca, México.
María Del Carmen López Zermeño
Departamento Salud Pública, Instituto Regional de Investigación en Salud Pública del [CUCS] Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, México.
María del Carmen Alejandra Hernández Ceruelos
Departamento de Medicina y Maestría en Salud Pública de la, Universidad Autónoma del Estado de Hidalgo, Pachuca, México.
Jesús Carlos Ruvalcaba Ledezma *
Departamento de Medicina y Maestría en Salud Pública de la, Universidad Autónoma del Estado de Hidalgo, Pachuca, México.
*Author to whom correspondence should be addressed.
Abstract
Objetive: Determining the risk factors associated with acute renal failure in neonates.
Materials and Methods: A case-control study was carried out, in 65 cases of acute renal failure and 65 without acute renal failure in the Intensive Care Unit Neonatals (NICU) of a hospital in Pachuca Hidalgo, Mexico. The variables studied; prematurity, low weight, type I respiratory distress syndrome, perinatal asphyxia, sepsis, necrotizing enterocolitis, administration of vancomycin, amikacin, amphotericin, cefotaxime and water restriction. The information was collected from the data of the clinical records and the analysis was carried out in the Epi-info software. The statistical analysis, it was performed using non-parametric tests such as Chi2 and Fisher's Exact Test.
Results: Denote underweight with an OR 2, 95% CI. from 1.1 to 3.3 and <P 0.05 by Chi2 and Fisher's exact test. For; perinatal asphyxia with OR 2.1, 95% CI. from 1.3 to 3.4 and <P 0.05 through Chi2 and Fisher's exact test. For vancomycin administration OR 4.7, 95% CI. From 2.3 to 9.3 and <P 0.05 by Chi2 and Fisher's exact test. For water restriction OR 2, 95% CI. From 1.2 to 3.3 and <P 0.05 by Chi2 and Fisher's exact test.
Conclusion: A significant association was found between acute renal failure with low weight, perinatal asphyxia, administration of vancomycin and water restriction.
Keywords: Acute renal failure, perinatal asphyxia, vancomycin administration, water restriction