Serratia marcescens Meningitis: Neonatal Case
F. Tahiri *
Neonatal Intensive Care Unit, University Hospital Center Mohammed VI, Marrakech, Morocco and Health, Childhood and Development Faculty of Medicine Research Team, Cadi Ayyad University, Marrakech, Morocco.
A. Lalaoui
Neonatal Intensive Care Unit, University Hospital Center Mohammed VI, Marrakech, Morocco and Health, Childhood and Development Faculty of Medicine Research Team, Cadi Ayyad University, Marrakech, Morocco.
D. Kaouani
Neonatal Intensive Care Unit, University Hospital Center Mohammed VI, Marrakech, Morocco and Health, Childhood and Development Faculty of Medicine Research Team, Cadi Ayyad University, Marrakech, Morocco.
F. Bennaoui
Neonatal Intensive Care Unit, University Hospital Center Mohammed VI, Marrakech, Morocco and Health, Childhood and Development Faculty of Medicine Research Team, Cadi Ayyad University, Marrakech, Morocco.
N. El-Idrissi Slitine
Neonatal Intensive Care Unit, University Hospital Center Mohammed VI, Marrakech, Morocco and Health, Childhood and Development Faculty of Medicine Research Team, Cadi Ayyad University, Marrakech, Morocco.
N. Soraa
Microbiology Department, University Hospital Center Mohammed VI, Marrakech, Morocco.
F. M. R. Maouainine
Neonatal Intensive Care Unit, University Hospital Center Mohammed VI, Marrakech, Morocco and Health, Childhood and Development Faculty of Medicine Research Team, Cadi Ayyad University, Marrakech, Morocco.
*Author to whom correspondence should be addressed.
Abstract
Serratia marcescens belongs to the Enterobacteriaceae family, commonly found in water, soil, animals, insects, plants. Although Serratia marcescens has low virulence, it causes nosocomial infections and outbreaks in extremely immunocompromised or critically ill patients, particularly in intensive care units, particularly neonatal units. This pathogen causes a wide range of clinical symptoms in newborns, including keratitis, conjunctivitis, urinary tract infections, pneumonia, surgical site infections, sepsis, bloodstream infection, and meningitis. The bloodstream is the most commonly infected location, followed by the respiratory tract and the gastrointestinal tract. Serratia marcescens strains implicated in epidemic events have often proven to be multiresistant. Indeed, this species has an inherent resistance to multiple antibiotic families. Often, the particular source of infection cannot be determined. However, infected hands of healthcare professionals are thought to be a key vector for its spread. Infection of the central nervous system by this bacterium in the neonatal period leads to serious neurological sequelae with high mortality interest of early and adequate management. Through our work we report the clinical presentation, the positive diagnosis as well as the therapeutic management and the evolution of a newborn having presented a meningitis with Serratia marcescens complicated by ventriculitis.
Keywords: Newborn, neonatal intensive care unit, epidemic, meningitis, Serratia marcescens, ventriculitis, external bypass, antibiotic therapy