Study Progress of Coronary Artery Damage in Kawasaki Disease
Rong Lu
The Department of Pediatrics of Yan’an University Affiliated Hospital, China.
ChunYan Gao
The Department of Pediatrics of Yan’an University Affiliated Hospital, China.
Bing Zhang
The Department of Pediatrics of Yan’an University Affiliated Hospital, China.
Fuyong Jiao *
Children's Hospital of Shaanxi Provincial People's Hospital No. 256, Youyi West Road, Xi'an, Shaanxi Province, China.
*Author to whom correspondence should be addressed.
Abstract
Kawasaki Disease (KD) is a vasculitis of unknown etiology commonly seen in infants and children. Children with Kawasaki disease are at risk for serious cardiovascular sequelae, especially coronary artery abnormalities, which can lead to myocardial ischemia, myocardial infarction, and sudden death. Coronary artery lesions (CAL) caused by Kawasaki disease has become one of the common acquired heart diseases in children in some countries and regions. This article reviews the current research progress on the mechanism, risk factors and treatment of coronary artery damage in Kawasaki disease, aiming to improve the long-term prognosis of vascular health management in children with KD, in order to provide references for clinicians.
Keywords: Kawasaki disease, coronary artery damage, risk factors, mechanism, heal