Transient Anti PM-Scl75 Antibody Positive Acral Ischemia Syndrome in a 15 Years-Old Girl
Stefan Bittmann *
Department of Pediatrics, Ped Mind Institute (PMI), Hindenburgring 4, D-48599 Gronau, Germany and Shangluo Vocational and Technical College, Shangluo, 726000, Shaanxi, China.
Elisabeth Luchter
Department of Pediatrics, Ped Mind Institute (PMI), Hindenburgring 4, D-48599 Gronau, Germany.
Elena Moschüring-Alieva
Department of Pediatrics, Ped Mind Institute (PMI), Hindenburgring 4, D-48599 Gronau, Germany.
*Author to whom correspondence should be addressed.
Abstract
In 1862, the French doctor Maurice Raynaud published his dissertation in Paris titled "Sur l’asphyxie locale et la gangrène symétrique des extrémités" (On local asphyxia and symmetrical gangrene of the extremities). In it, he described a series of cases in which there were episodes of acral ischemia. The phenomenon later named after him typically involves changes in skin color from white to blue-livid to red, caused by a vasospasm of acral arteries (white phase) followed by reactive vasodilation. Acral ischemia is present in different clinical conditions as stated in this manuscript. We report a case of a transient anti PM-Scl75 antibody positive acral ischemia syndrome in a 15 years-old girl.
Keywords: Thrombosis, embolism, blockage, oxygen deprivation, ischemia