Successfully Treated Case of Non-Typhoidal Salmonella Meningitis in an Otherwise Healthy 5 Months Old Infant: A Case Report
Sana Hannan
Department of Pediatrics, The Aga Khan University Hospital, Karachi, Pakistan.
Abdul Ahad Sohail *
The Aga Khan University Hospital, Karachi, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Acute bacterial meningitis in infants is a medical emergency requiring prompt diagnosis and early institution of empirical antibiotic therapy. Non-typhoidal salmonella (NTS) is a major cause of uncomplicated infectious diarrhoea worldwide; however NTS meningitis is extremely uncommon beyond the neonatal period with very few cases being reported in the literature and has been associated with increased mortality and morbidity with mortality rates of up to 40-70% reported in recent studies. NTS being a facultative intracellular organism does not respond to conventional antibiotic therapy and therefore failure and relapse rates are higher particularly with meningitis. We report a rare case of a five month old infant with non-typhoidal salmonella meningitis who was successfully treated with prolonged duration of antibiotic therapy.
Keywords: Non-typhoidal salmonella, meningitis, infant