A Retrospective Study of Pediatric Urinary Tract Infections of Tamatave University Hospital Center, Madagascar
Arthur Bien Aimé Ratsimbazafy
Department of Mother and Child, Pediatric Service, Faculty of Medicine, University of Tamatave, Madagascar.
Andry Maharo Andrianarivelo *
Department of Biology, Microbiology Laboratory of the Joseph Ravoahangy Andrianavalona University Hospital Center, Faculty of Medicine, University of Antananarivo, Madagascar.
Narison Mbolanirina Lala Rakotomahefa
Department of Mother and Child, Pediatric Service of Universitary Hospital Center Befelatanana, Faculty of Medicine, Antananarivo, Madagascar.
Heriniaina Rakotoarisoa
Department of Mother and Child, Pediatric Service, Faculty of Medicine, University of Tamatave, Madagascar.
Van Cuong Miora Anissa
International SOS Clinic, Tamatave, Madagascar.
Jean De La Croix Rasolonjatovo
Department of Mother and Child, Pediatric Service, Faculty of Medicine, University of Tamatave, Madagascar.
Norotiana Rabesandratana
Department of Mother and Child, Pediatric Service, Faculty of Medicine, University of Majunga, Madagascar.
*Author to whom correspondence should be addressed.
Abstract
Urinary tract infection (UTI) is very common in children. The future of kidney function depends on its management.
Our objective was to investigate the epidemio-clinical, bacteriological and therapeutic profile of UTIsin the Pediatric Department of Tamatave University Hospital Center, Madagascar for better care of children.
Methods: This is a retrospective and descriptive study that was carried out in the Pediatrics Department of Tamatave University Hospital over a three-year period from January 1, 2017 to December 31, 2019. The parameters retained and studied were age, gender, clinical signs, pathogens identified with the results of the antibiotic susceptibility tests and the treatments received.
Results: The frequency of UTI was 7.46%. The average age was 11.21 months, with extremes of 2 to 120 months. Fever was the main symptom found (80.95%) followed by urinary signs. Escherichia coli was the most frequently isolated bacteria (61.90%). Almost all of the isolates found (98%) were resistant to amoxicillin, tetracycline and cotrimoxazole. Ceftriaxone alone was the most used (44.44%).
Discussion: This study suggests that gentamicin and ceftriaxone (even though ESBLs were found) should be included in the treatment protocol for UTIs in the absence of an antibiogram, which is not always available in our context.
Keywords: Urinary tract infection, paediatrics, Escherichia coli, gentamicin, Tamatave