Incidence of Neonatal Convulsion/Seizures Associated with Primary Disturbance of Calcium, Phosphorus, and Magnesium in University of Port Harcourt Teaching Hospital (UPTH)
Harrison Ogheneochuko Eruotor
Department of Biochemistry, Faculty of Sciences, University of Port Harcourt, Port Harcourt, Choba, Rivers State, Nigeria.
Ukoro Blessing *
Department of Human Physiology, College of Health Sciences, University of Port Harcourt, Port Harcourt, Choba, Rivers State, Nigeria.
Akpotu E. Ajirioghene
Department of Pharmacology, PAMO University of Medical Sciences, Elelenwo, Rivers State, Nigeria.
C. Awarajih Uwaezuoke
Department of Biochemistry, Faculty of Sciences, University of Port Harcourt, Port Harcourt, Choba, Rivers State, Nigeria.
Nduka Ignatius Chinonye
Department of Health Services University of Port Harcourt, Port Harcourt, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Neonatal seizures are abnormal electrical discharge in the neonates that usually manifest as stereotyped muscle activity of autonomic change. Seizure occur in up to 1.4% of mature infant and 20% of pre-mature infant. Neonate in university of Port Harcourt Teaching Hospital were used for the study, 86 blood samples were collected from the children department, the children include both male and female within the Age range of I day to 7 day. Out of the total of 86 sample analyzed for calcium, magnesium and Phosphorus from the results obtained from both calcium and magnesium failed below the reference value, that indicate that calcium and magnesium where the major causes of the neonatal seizures.
Keywords: Neonatal seizure, electrolytes, calcium, magnesium